But he added that the Argentine's presence would not affect his game plan.
"But risking the fitness of any player - Messi or anyone else - I'm not really in favour of it because they inevitably play with some fear, and games like tomorrow can not be played with fear".
Messi is a doubt for the first leg at the Camp Nou on Wednesday after feeling discomfort in his thigh during Sunday's draw with Valencia.
Barcelona forward Ousmane Dembele is unlikely to be fit for the game, as he is still recovering from a hamstring injury.
"There is a training session and we will see how he is, whether he can do it and whether he is in the right condition". Valverde said he would wait to make a decision but optimisim is increasing at the Camp Nou ahead of the game on Wednesday.
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Asked whether Vinicius' recent displays made him undroppable, Solari replied more shortly that: "Nobody is undroppable in football".
"It's always good when the best players get to play every game, but whether or not he plays will not influence the way we prepare for the game at all", Solari said.
Fourth-placed Sevilla missed the chance to overtake Real Madrid as they suffered a surprise 1-0 defeat at struggling Celta Vigo.
"In a semifinal between Barca and Madrid there's no favourite". We have the player we believe is the best in world but they also have great players.
"They were in a completely different place then, which needs to be taken into consideration", he said of Madrid, who have won seven of their last eight matches in all competitions. "If Messi's ready he will play, if he's not he won't". The Madrid coach assured that "so much more [rest] is curious, but we don't come up with [the scheduling]", in a clear reference to La Liga.