Second-placed Tottenham had already blinked first before this match kicked off, losing 3-1 at home to Wolves, and City, now 10 points adrift, can not afford to do the same at Southampton on Sunday with Jurgen Klopp's side arriving on Thursday.
Manchester City will climb back into second place if it beats Southampton on Sunday, but the gap to the leader would still be seven points ahead of their meeting at the Etihad Stadium on Thursday.
"I hurt myself giving everything for this team and I think that when I came back from injury, I deserved an opportunity", Moreno said to Cadena Ser.
"I mean, how many times can you mess up and still think you deserve to play?"
Guardiola, though, refused to get too despondent, pointing out that City's performance over the first half of the season has largely been positive.
The Spaniard has made just two appearances in the Premier League so far this season and recently opened up on an interview that he is clearly frustrated with the lack of playing time.
"I am happy if he chooses me because like I said we all want to play but it is not possible to play every game because of the way we play with lots of running, high intensity, then you have to use the squad, especially around this part of the season".
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"The people say, "You will win today" but first I have to run".
"It happened in Barcelona, where it was stable, or Bayern Munich, where we won a lot of titles but I failed because I did not win the Champions League".
Emery took the summer to recruit two central midfielders in the form of Lucas Torreira and Mateo Guendouzi and the duo have swiftly settled to the new surroundings with the former evolving into a major player in the club's top-four pursuit. That can happen. Tomorrow we can lose, then again at Liverpool and again in the FA Cup.
"If you remember at the start of the year Liverpool were still, they weren't struggling to be top four, but they were fourth and they nowhere near where they are now". We couldn't stop this moment.
The Gunners have looked solid enough when they have their best defensive unit fit and available. We have to run.
'We expect the most hard challenge that is possible.