Most of those targeted this week were past or present USA officials, but packages also were sent to actor Robert De Niro and billionaire George Soros. And the NYPD described that device yesterday as an explosive device.
A law enforcement official told CNN that the initial examination of all of the devices shows them to be constructed similarly.
"As far as a hoax device, we're not treating it that way", said Police Commissioner James O'Neill.
The Soros package also had the return address of Wasserman Schultz, a former party chairwoman, a law enforcement source and a federal source briefed on the investigation said Wednesday.
When Trump was campaigning for president in 2016, the New York-born actor slammed the Republican candidate as "blatantly stupid", "totally nuts" and an "idiot".
CNN has been a frequent target of Trump's "fake news" barbs, and a "CNN sucks" chant broke out at a Monday campaign rally.
The first inkling that there might be a serial bomber came Wednesday morning when the Secret Service revealed that it had "intercepted two suspicious packages addressed to Secret Service protectees", who were Clinton and Obama. The bombs were all shipped in the same envelope with the same stamps and same labels.
At the news conference, Cuomo disclosed that a device was sent to his Manhattan office and that it was being handled.
"Unfortunately, I think Donald Trump, too often, has helped to incite some of these feelings of anger, if not violence, when he points to acts of violence or also talks about swinging at somebody from the press, the media", he said. "We'll keep you posted on that", Sciutto said.
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The complaint also included details suggesting Sayoc's antipathy toward the people and organizations targeted, including CNN, where one packaged was found and another addressed.
On Tuesday, one of the law enforcement officials said the motive of the would-be Soros bomber or bombers remained unclear, adding that there had not yet been any claim of responsibility.
Authorities have branded the parcel bombs, coming less than two weeks before national elections that could alter the balance of power on Capitol Hill, as an act of terrorism, though they have declined to say whether the devices were built to be functional.
New York's leaders pleaded for civility in America's political discourse Wednesday as Democrats and progressives across the country found themselves confronting a barrage of crude package bombs aimed squarely at the critics and rivals of U.S. President Donald Trump.
Wray declined to say whether the devices could have detonated, saying that investigators are "still trying to determine whether or not they were functional". The CNN package was addressed to former CIA Director John Brennan, who has publicly clashed with Trump and is a regular television contributor. Sources previously told CNN that investigators believed some of the packages might have originated in Florida and that investigators were there, chasing down leads. It was compact, perhaps about the length of a wooden spoon, and contained wires and a black pipe, officials said. Last week an association representing White House correspondents accused Trump of "cheerleading" violence against the media after the president applauded an assault by a congressman on a reporter.
White House spokeswoman Sarah Huckabee Sanders condemned the "terrorising acts" and said "anyone responsible will be held accountable to the fullest extent of the law". And the way to stop that is to turn back the other way, to bring down the temperature, to end any messages about the use of violence against people we disagree with.
The packages had numerous hallmarks of suspicious mail, including large block lettering and excessive postage aimed at making it harder to track, said Matthew Doherty, who formerly led the U.S. Secret Service's National Threat Assessment Center.
Waters, whom the president has denigrated as a "low-IQ individual", reported Wednesday afternoon that she was the target of a suspicious package.