"Judge Kavanaugh has said that sitting presidents can not be indicted, can not be prosecuted, should not be investigated and should have the authority to fire a special counsel at will".
Saturday's vote is likely to come down to just a handful of undecided senators.
Murkowski said she would vote no on his confirmation.
The West Virginia Democrat declined comment to reporters as he boarded a Senate subway, saying he would release a statement on the Kavanaugh nomination later in the day. With Indiana's Joe Donnelly and North Dakota's Heidi Heitkamp having announced that they are definite "no" votes, Manchin remains the sole Democrat who might help to save Kavanaugh's nomination.
Collins' speech was immediately interrupted by protesters in the Senate gallery, who chanted "vote no", indicative of the huge pressure she faced to oppose Kavanaugh's nomination.
In it he says, "if confirmed by the Senate to serve on the Supreme court, I will keep an open mind in every case and always strive to preserve the constitution of the United States and the American rule of law".
The Senate Judiciary Committee confirmed his nomination on party lines, after which his nomination moved to the Senate floor.
She has been lobbied by sexual assault survivors to vote against the judge and represents a state with the highest sex crime rate by far in America, according to Federal Bureau of Investigation data.
Both he and Collins attempted to express a belief that Dr. Blasey Ford was assaulted, but not by Kavanaugh. She said that though she "will be a no tomorrow", she will vote "present" out of respect for Sen.
Interpol asks China for info on agency’s missing president
Al Jazeera's Adrian Brow, reporting from Beijing , said China's silence is a "reflection of how sensitive this case is". Has Meng Hongwei angered China? The 64-year-old was elected as the president of Interpol in November 2016.
Amy Schumer Was One Of Hundreds Arrested At Anti-Kavanaugh Protest
Still, protestors, including celebrities Amy Schumer and Emily Ratajkowski , say they aren't giving up hope just yet. Video from the scene shows the two actresses being detained after an officer asked if they want to be arrested .
Chinese Wary as Putin Visits India for Arms Deal
Last year India and China had a military standoff over a Himalayan plateau claimed by Beijing and Bhutan, a close ally of India. Putin said the two countries have agreed to step up cooperation in combating the menace of terrorism and drug trafficking.
A final vote on whether Judge Kavanaugh will join the nine-member panel is scheduled for Saturday.
In explaining her vote to reporters, Murkowski said on Friday that she had not come to a decision on how she would vote until walking into the Senate floor that morning.
"I believe that Brett Kavanaugh is a good man".
But Collins's support is expected to give Kavanaugh enough votes to clear the Senate if the rest of the Republican caucus holds firm.
Republicans hold 51 seats in the Senate and changed Senate rules past year to end filibusters for Supreme Court nominees. "The tactics have energized our base", he said, adding: "I want to thank the mob, because they've done the one thing we were having trouble doing, which was energizing our base".
"I have been wrestling to really try to know what is fair and what is right and the trust is that none of this has been fair". Eventually, Flake voted to recommend Kavanaugh for confirmation but conditioned his final vote on the FBI conducting a seventh background investigation on Kavanaugh.
The Friday cloture vote limits further debate and Democrats' ability to filibuster the final vote.
"I do hope it reminds us that we can take very small steps to be gracious with one another and maybe those small, gracious steps can lead to more", Murkowski said Friday in announcing her intent.