McConnell called Kavanaugh "among the very best our nation has to offer." Sen.
Dr. Christine Blasey Ford, flanked by attorneys Debra Katz and Michael Bromwich, testifies during a Senate Judiciary Committee hearing on Capitol Hill, Sept. 27, 2018 in Washington.
Two other women also made accusations of sexual misconduct by Kavanaugh in the 1980s.
Sen. Jeff Flake, R-Ariz., who has repeatedly battled Trump and will retire in January, said he'd vote for Kavanaugh's confirmation "unless something big changes".
Banks also hit out at a Republican talking point following Ford's testimony last week that she wasn't aware there was an offer from committee Republicans to fly to California to interview her in her home state. But I think Sen.
But that evolved into a late-summer spectacle after Ford accused Kavanaugh of trying to rape her at an alcohol-infused high school gathering in 1982, when both were teenagers.
Murkowski said her decision was "agonizing" and she was "truly leaning" toward confirming Kavanaugh.
The Alaska senator expressed dismay at the acrimony in Kavanaugh's confirmation process and said on the Senate floor, "I am really anxious that this becomes the new normal, where we find new and even more creative ways to tear one another down, that good people are just going to say forget".
She used a court case from Washington state as an argument against Kavanaugh.
Still, she sent signals that Kavanaugh had cleared a hurdle by reassuring her that he believed the 1973 Roe v. Wade decision on abortion rights is settled law.
The first test vote on the nominee is due in a few hours. Protesters were also heard shouting from the Senate gallery during the roll call.
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Row breaks out over Federal Bureau of Investigation report on Kavanaugh
That may have been the case, but it also may have imposed restrictions requested by Senate Republicans. She said the demonstrators were processed in a park outside the Russell Senate Office Building.
About 100 anti-Kavanaugh protesters climbed the Capitol's East Steps as the vote approached, pumping fists and waving signs, and U.S. Capitol Police officers began arresting some of them.
Coons said undecided senators ought to "weigh very carefully" the temperament Kavanaugh displayed during last week's hearing. He has a decent sized lead in the polls against the Republican, Patrick Morrisey.
"We will see what happens tomorrow", said Murkowski.
"I think that the tenor and the content of the letter is not a radical statement", said Mary Davis, a United Kingdom law professor.
But she added that people must listen to the survivors of sexual assault, noting that she doesn't necessarily think Ford's allegations are false.
Minutes after Senator Susan Collins (R-ME) indicated that she will vote yes to confirm Brett M. Kavanaugh to the U.S. Supreme Court tomorrow, a crowdfunding effort raising funds to unseat her in 2020 crashed. That support all but assured Republicans of the votes they needed to push the nomination across the finish line.
Ryan in Redmond said that while he supports the judge, both the idea of a Kavanaugh confirmation and the idea of Kavanaugh losing out on the Supreme Court seat are "scary for both reasons".
In the pivotal moment on Friday, Mrs Collins, perhaps the chamber's most moderate Republican, proclaimed her support for Mr Kavanaugh at the end of a Senate floor speech that lasted almost 45 minutes.
Two key Republican senators said they were satisfied with the FBI's background investigation report on October 4, and said it didn't corroborate the claims of the women accusing Kavanaugh of misconduct.
"My heart goes out to anyone who has experienced any type of sexual assault in their life", Mr Manchin said.
But he said he believes Kavanaugh will "determine cases based on the legal findings before him".