Hurricane Florence, which is approaching the eastern United States and Super Typhoon Mangkhut which is heading towards the northern Philippines and may also hit Hong Kong.
Meanwhile, the USA east coast braces as Hurricane Florence barrels towards the Carolinas, expected to make landfall late September 14 or early September 15.
According to the Global Disaster Alert and Coordination System, up to 43.3 million people may be affected by Mangkhut.
Typhoon Mangkhut, which has already blasted through the Northern Mariana Islands and Guam, is speeding across the Pacific with winds that can gust as high as 255 kilometres (160 miles) per hour.
Philippines' Office of Civil Defence chief Ricardo Jalad said low-lying areas in northern regions would be evacuated on Thursday.
The Philippine Red Cross estimates three million Filipinos live in the direct path of Mangkhut, communications officer Mary Joy Evalarosa told AFP. "According to the forecast track, it's going to maintain a super typhoon status for the rest of its journey to the South China Sea".
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PAGASA defines a super typhoon as a weather disturbance carrying more than 220 kilometers per hour (kph) of maximum center winds.
Schools were shuttered and some farmers took to their fields to start early harvest of corn and rice that could be ruined by flooding. Cathay Pacific encouraged passengers travelling this weekend to and from Hong Kong to re-book and the airline would waive the fees.
A prayer for deliverance from calamities will be recited in Catholic churches across the Philippines starting Thursday as the country braces for Typhoon Ompong (international name: Mangkhut), a powerful storm expected to hit northern Luzon.
While Mangkhut is now stronger than Hato -- also known as Tropical Storm Isang -- or Haima it is likely to decrease in strength as it nears southern China, particularly if it crosses land over northern Luzon, which will slow the storm, according to Guy, the meteorologist.
Floods, landslides and huge waves could put millions at risk as Typhoon Mangkhut hurtles towards the Philippines and Hong Kong. Typhoon Haiyan left more than 7,300 people dead or missing and displaced over 5 million in the central Philippines in 2013. Yolanda brought center winds averaging 235 kph. Hot weather is forecast on Saturday, with heavy rain expected throughout Sunday and Monday.