The 900-page report released yesterday - considered the most comprehensive of its kind - said 300 Roman Catholic priests committed abuse with impunity.
Cardinal Daniel N. DiNardo, the USCCB's president, called the failure of bishops on the issue of child sexual abuse a "moral catastrophe".
And next weekend Pope Francis will be travelling to Ireland, which is also no stranger to sex abuse by priests.
The Pennsylvania grand jury investigation detailed accusations against 301 priests of sexually abusing more than 1,000 children and adolescents over a period of 70 years.
The lengthy report investigates clergy sexual abuse dating back to 1947. As the grand jurors note, priests and other Catholic leaders victimized boys and girls, teens and pre-pubescent children.
Some victims were plied with alcohol and groped or molested while others were raped.
The Vatican vowed to hold accountable sexually abusive priests and bishops who enable them to continue to prey on minors.
Any in-depth investigation of the McCarrick case is likely to shed light on the timetable for when senior Catholic officials in the US and at the Vatican know about the multiple allegations against McCarrick.
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Victims can report abuse on the Pennsylvania Attorney General's Abuse Hotline at 888-538-1543.
In a statement, it said the Church wanted to listen to the victims to "root out this tragic horror".
Even if a priest was abusing children, they were allowed to keep their housing and living expenses.
The Vatican on August 16 broke its silence and responded for the first time on the Pennsylvania grand jury report that detailed widespread and decades-long sexual abuse by clergy, as well as the systemic coverup efforts of church officials.
In reference to the intricate cover-up of these numerous abuse reports, the grand jury report also alleges that the church had their own "playbook for concealing the truth". "The church must learn hard lessons from the past, and there should be accountability for both abusers and those who permitted abuse to occur". "And sorrow, disgust, outrage - these are righteous feelings, the stirrings of the conscience of a people scandalized by the bad reality that too numerous men who promised to protect their children, and strengthen their faith, have been responsible for wounding both".
In some cases, church leaders alerted the Vatican about allegations against priests in their dioceses - as well as their decisions to let them to stay on in their roles.
"During my tenure, we acted... very appropriately with many times removal from ministry, totally and completely", he said.