The result was a 3&2 defeat that means Dustin Johnson will head to the Masters next week with his 14 month reign at the summit intact.
Watson had to change his plans, though, once he beat Kiradech Aphibarnrat in Saturday afternoon's quarterfinals.
"Me donating money to the Children's Hospital, that's the biggest trophy I've ever been a part of", Watson said.
"You're constantly getting questions about it with the media but I need to be mentally stronger than that, and understand that it's just a match".
But victory in Sunday's World Golf Championships Dell Match Play helped remind Watson of his unique talent as he joined only four other players to have won multiple majors and multiple WGC events, the second most prestigious group of tournaments.
Kisner was chasing the biggest title of his career, having won PGA crowns at Colonial previous year and Sea Island in 2015.
Naturally, the emotional Watson started blubbering at the end as he hugged his mother, Molly.
"You're really good at this game", she told Watson. 'I've never seen anyone conjure shots with their hands and footwork like he does.' Watson was controversially left out of the last American Ryder Cup team but will surely be in Paris this year.
Watson has always been a player known for wearing his emotions on his sleeve.
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"So it was a very low point in my golf career". He was ready to walk away from the game and contemplated retiring. "I can sit here and make up stories all day, but it's absolutely remarkable that I'm able to life a trophy like this". "Every time I looked up, there was nowhere to look", Kisner said.
"I happen to be 39 now but I'm just a kid playing golf and having fun with it. Quit eating chips and here we are". She has four LPGA Tour victories, including the 2009 U.S. Women's Open. "There's one that sometimes can get a little cocky out there and a little bit negative - complain about this or that.a course that doesn't fit his eye". You can't get time back. "And when good Bubba is around, watch out".
Thomas said he was too consumed with what was at stake in the semifinals - the No. 1 ranking.
As Watson approached the sixth tee box, he turned to a reporter and said, "Hey, no matter what - I was beating No. 1 at one point". Even in that moment, whether he ended up winning or losing, Watson wasn't afraid to let his mind realize what was going on.
A Callaway representative said it was just "Phil being Phil" and tinkering with his current setup, but it's a situation worth monitoring going forward, especially when you consider it's been three years since PM Grind launched.
He won six of the first seven holes to take a 6-up advantage.
Watson started using the putter at the AT&T Pebble Beach Pro-Am but went back and forth with the loft, starting with 3.5 degrees at Pebble Beach before settling on 4.5 degrees at the Genesis Open. Kisner then hit just inside the hazard and had to play up short of another hazard.
BUBBA WATSON could have been working in his candy store, instead of savouring the sweet taste of victory at the Dell World Match Play. I mean everybody who's a golf fan loves it.
Heading to the Masters, which he describes as the "greatest sporting event in golf history", he is determined to keep his head down - "look like a zombie" - and not get distracted by the hype surrounding him.