Four people were injured in the attack.
The bomb, targeting security chief convoy in Rushdy district, was planted under a auto and went off when the convoy passed by it, according to a statement by the ministry of interior.
State-run MENA news agency said the public prosecutor has ordered an investigation into the incident.
Two policemen were killed in Alexandria, Egypt, on Saturday by a bomb that went off as a convoy containing the city's security chief passed by.
The bomb attack struck the convoy of Alexandria's security chief General Mostafa al-Nimr.
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The blast comes just days ahead of Egypt's presidential election, in which President Abdel-Fattah el-Sissi is virtually certain to be re-elected.
Footage from the site of the explosion shows a vehicle engulfed in flames and black smoke billowing from it.
Egypt has been suffering a wave of terrorist attacks that killed hundreds of policemen and soldiers since the military ousted former Islamist President Mohamed Morsi in July 2013 in response to mass protests against his one-year rule and his now-outlawed Muslim Brotherhood group.
There was no immediate claim of responsibility for the attack, which came two days before Egyptians begin voting in a presidential election and amid a wide-scale security campaign against ISIL militants in the north Sinai Peninsula.
It has also killed scores of members of Egypt's minority Coptic Christian community in church bombings and shootings.