The letter slammed the attack as "a continuation of the crimes committed on daily basis by these terrorists against the citizens in Damascus", saying they have fired more than 1,500 shells in the past seven weeks and left hundreds dead and wounded.
Even though these attacks have claimed lives of adults and children alike, the regime maintains these are "precision strikes". France, a permanent member of the U.N. Security Council, described the bombardment as a serious violation of worldwide humanitarian law.
The Kremlin said on Wednesday that Western allegations the Russian Air Force was responsible for civilian deaths in the rebel-held district of eastern Ghouta outside the Syrian capital Damascus were groundless.
"Without the support of these two allies, Assad's regime would not be where it is today, and undoubtedly, without this support, this regime would have to show more readiness to negotiate in the United Nations (peace) process", the German government spokesman added.
Casualties in a Syrian government assault on the rebel stronghold to the east of Damascus are thought to include as many as 100 children, with several hospitals reported to have been hit. He said the mediation was between insurgents and Moscow, the Syrian government's key ally, but did not elaborate.
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"They targeted everything: shops, markets, hospitals, schools, mosques, everything", Dr Bassam said.
The UN has repeatedly called for a month-long ceasefire across Syria's front lines, from Eastern Ghouta to the Kurdish enclave of Afrin in the northwest, which Turkey threatened on 20 February to lay siege to in the coming days. Russian Federation has suggested that the United Nations Security Council should hold an emergency session over the situation in Eastern Ghouta, Damascus' suburb, on Thursday.
The medical personnel in Eastern Ghouta can't cope with the high number of injuries.
The ICRC and the Syrian Arab Red Crescent accessed Eastern Ghouta in December to facilitate the evacuation of 29 wounded patients.
The Union of Medical Care and Relief Organisations, a group of foreign agencies that fund hospitals in opposition-held parts of Syria, said eight medical facilities in eastern Ghouta had been attacked on Tuesday.