The Houston Texans and general manager Rick Smith seemed to put all of their eggs in the Brock Osweiler basket two offseasons ago, which put the future of O'Brien in limbo because he's been expected to make the playoffs and win games there.
ESPN's Adam Schefter tweeted that Tiffany Smith has been undergoing treatments in Arizona; Rick Smith has been traveling back and forth to care for her.
Smith reportedly has a close relationship with Texans owner Bob McNair and his son, team vice chairman and chief operating officer Cal McNair. However, the most important thing at the moment is the health of Smith's wife.
Smith has served as Houston's general manager since 2006 and oversaw all personnel decisions. Smith was given a four-year contract extension in July 2016.
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O'Brien has one season remaining on the five-year contract he signed when taking over as head coach of the Texans in 2014.
In the statement, Smith said that it was hard decision and that he is grateful for the support of Texans owner Bob McNair and his family, via Amy Palcic from the team's PR staff.
"I don't have any comment on that", O'Brien said Sunday. He also would come with Bill Belichick's approval from his days on the Patriots staff. O'Brien is 31-32 in four seasons.
Dec 17, 2017; Jacksonville, FL, USA; Houston Texans head coach Bill O'Brien looks on in the game against the Jacksonville Jaguars during the first half at EverBank Field.