Clooney will direct and star in the six-episode series, based on U.S. author Joseph Heller's darkly comedic 1961 novel Catch-22, for Viacom Inc's Paramount Television and Anonymous Content, shooting in early 2018, the studio said.
The protagonist of the work is a pilot of the US Air Force bomber regiment, Captain Yossarian, who loses his entire crew in Italy.
Clooney and Grant Heslov will direct. Richard Brown and Steve Golin will executive produce on behalf of Anonymous Content along with Clooney and Heslov via Smokehouse Pictures.
Clooney previously starred on the small screen in Roseanne and The Facts of Life, but he made his breakthrough as the much-loved Dr Doug Ross in the medical drama ER.
Clooney will play Colonel Cathcart in the series, an army commander during World War II who is eager to climb the ranks at any expense.
Clooney's directing credits include The Ides of March, The Monuments Men and Suburbicon, which hits United Kingdom cinemas on 24th November and stars Matt Damon and Julianne Moore.
Clooney and Heslov are repped by CAA. Julia Roberts also signed on to star in Sam Esmail's take on popular podcast Homecoming, which landed at Amazon with a two-season pickup.
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