"The last race I ran was 9.95sec, which shows I'm going in the right direction", he said.
"That's the plan", De Grasse said ahead of the meet.
He recorded the fastest time of the year, albeit a strongly wind-assisted 9.69sec in Stockholm in June.
On the eve of his final two races - the 100m and the 4x100m relay - the 30-year-old told Reuters TV that he would be as focused on the finish line as always.
Beyond the unbelievable things Bolt did throughout his career, two record runs by other athletes stand out over the past decade: David Rudisha setting a world record to win the 800 meters at the London Olympics and South Africa's Van Niekerk running in the outside lane at the Rio Games previous year to win gold with a 400-meter world record.
"I've just spent the day talking with what we call Athletics Connect, with people from 214 federations, talking about the big issues for our sport", Coe said.
"I can't approach it any different".
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What he does best is win - a trait he shares with Bolt.
"Every year you find something else to motivate you", he said. The Puma CEO is taking him to watch Arsenal play Chelsea in Sunday's Community Shield at Wembley Stadium.
Bolt, who had just finished his Puma press conference on Tuesday, looked surprised as his parents appeared from backstage to present the star with the spikes made exclusively for his last competitive appearance in London.
De Grasse has sustained a hamstring tear this week and the injury is going to cause him to give London a miss.
The defending 400m world champion said while he had no immediate plans to remove the one-lap sprint from his repertoire, the shorter distances would receive more attention in future. Each final came with a US$50,000 first-place prize. He explained how his motivation to keep putting his body through such a punishing regime was renewed each year by resetting his goals - with one often created for him by a casually "disrespectful" remark from one of his opponents.
"I mean, what he has achieved for track and field alone these last few years has been massive".
"I expect Andre comes out stronger from this, and we're definitely going to learn, us as a team and me as a coach, I'm going to learn a lot from what's gone on here in the last few days".