Warplanes on Saturday struck the Syrian town where a chemical attack had killed scores of people earlier this week, as Turkey warned that a retaliatory US missile strike on a Syrian air base would only be "cosmetic" if greater efforts are not made to remove President Bashar Assad from power.
U.S. Treasury officials say they are preparing sanctions in response to the chemical weapons attack, though the Syrian government is already buried under U.S. sanctions.
US Ambassador to the United Nations Nikki Haley said in an interview that she sees regime change in Syria as one of the Trump administration's priorities in the country wracked by civil war.
However, he stopped short of accusing Russian Federation of being directly involved in the planning or execution of the attack, saying he had not seen "any hard evidence" to suggest the country was an accomplice to Mr Assad. Graham said the Syrian leader intentionally did so to send a signal back to the US commander in chief.
Russian Foreign Minister Sergei Lavrov and U.S. Secretary of State Rex Tillerson spoke by phone on Saturday about the situation in Syria after the U.S. strikes on a Syrian air base, the Russian ministry said in a statement.
A statement released by the Russian Foreign Ministry on Sunday noted that during Johnson's trip, talks had been scheduled on an "entire spectrum of global problems" and also over Moscow-London ties.
The hope, he said, is that "we can navigate a political outcome in which the Syrian people, in fact, will determine Bashar al-Assad's fate and his legitimacy".
It prompted President Donald Trump to retaliate by firing 59 cruise missiles at the Syrian airbase where the USA believes the gas attack was launched.
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It said the strike was believed to have been carried out by Russian planes, which operate in support of the Assad regime.
"It agreed to be the guarantor of the elimination of the chemical weapons, and why Russian Federation has not been able to achieve that is unclear to me", Tillerson said.
Hassan Rouhani and Vladimir Putin, the Iranian and Russian presidents, said on Sunday that US airstrike against Syria was an act of invasion which ran contrary to global law and the United Nations charter.
"So there's multiple priorities", she said.
Trump's national security adviser, H.R. McMaster, said today that he saw the situation as a "great opportunity" for Russian Federation.
"We're asking and calling on Bashar al-Assad to cease the use of these weapons".
Graham said he supports the president's decision to order the strikes, but wants to see more from the administration on Syria.
However, US Secretary of State Rex Tillerson will visit Moscow as planned after the G7 meeting in Italy on April 10-11.