Old Trafford erupted in the seventh minute when Ander Herrera won the ball in midfield, possibly by using his hand, and delivered an inch-perfect pass into the path of Marcus Rashford, who outpaced Luiz and fired low into the far corner of the net.
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For United the victory puts them back in contention for a top-four finish with them now sitting just four points behind fourth place Manchester City, who they face at Eastlands in 10 days time. "I think we played really well, a very solid performance", said Mourinho.
Neville told Sky Sports after the game: "It was a brilliant performance. The kid played very well and again".
Jose Mourinho's squad avenged its 1-4 humiliation at Chelsea's Stamford Bridge in the first half of the season and the 0-1 FA Cup quarter-finals defeat against Antonio Conte's Blues.
"We did that at Stamford Bridge when we played with 11, with 10 it was more hard and today we controlled". "At this stage of the season, if we win all our games then we are going to find ourselves in the top four and that is how we have to approach the games. They showed more desire, more ambition, more motivation", said Conte.
"If we win our games it doesn't matter what Tottenham do".
"For us it is a fantastic target".
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"Yes, we didn't react well to it and we were poor", he added.
"We stay in a great position, but Tottenham are in good form and playing very well and with enthusiasm. We must have the same".
There hasn't been a player this exciting at Manchester United since an 18-year-old Cristiano Ronaldo signed for the club from Sporting back in 2003.
Controversy preceded the goal as replays suggested the midfielder had handled the ball in the build-up, but Herrera protested his innocence.
"I will always be thankful but football changes".
The Spain worldwide also contributed by doubling United's advantage with a deflected strike just four minutes after half-time. "We can be very happy".
One of the big discussion points of the game was whether Rahsford's rampant running to go with his goal, and how it made United so much livelier, should justify getting into the team ahead of the rested Zlatan Ibrahimovic.