The objective of the strike is ostensibly to protest prison conditions, to receive more visitation time with family and to end detention without trial, but a number of observers see the effort as part of a Barghouti run for PA leadership.
Barghouti, a leader of the 2000 Palestinian uprising, is serving five life terms after being convicted by an Israeli court of directing two shooting attacks and a bombing that killed five people.
The strike is led by Marwan Barghouti, a high-profile Fatah-linked prisoner, who is considered by some as a potential successor to President Mahmoud Abbas.
People hold banners during a rally in support of Palestinian prisoners in the West bank City of Bethlehem, Monday, April 17, 2017.
In 2011, Israel swapped more than 1,000 Palestinian prisoners for an Israeli soldier who had been held by Hamas for five years.
Others are detained under so-called Administrative Detention, which allows suspects to be held without charge for six-month intervals.
Israeli officials said some 1,100 prisoners joined the strike on Monday.
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He went on to highlight the importance of "internationalizing the issue of Palestinian detainees in global arena and exposing the racist policies of Israeli occupation against them".
Israeli officials are refusing to negotiate with hunger striking Palestinian prisoners, now on day 2 of their protest.
The essay asserted that "Israel has established a dual legal regime, a form of judicial apartheid, that provides virtual impunity for Israelis who commit crimes against Palestinians, while criminalizing Palestinian presence and resistance".
Jailed Fatah leader Marwan Barghouti (C) is accompanied by Israeli prison guards after a deliberation at Jerusalem Magistrate's court January 25, 2012.
Top Palestinian official Hanan Ashrawi called on the worldwide community to bring an end to the "inhumane" treatment of Palestinian prisoners, which she said was in violation of the Geneva Convention. Palestinians marked Tuesday as Prisoners' Day.
As reported by ABC News, the Israeli government has no current plans to enter talks regarding ending the Palestinians' hunger strike.
Riyad Mansour, the Palestinian ambassador to the United Nations, called the demonstrations a "peaceful expression of opposing occupation".
"My policy is that you can't negotiate with prisoners such as these". Nowhere is there any reference to Barghouti's leadership of the Palestinian terror group Tanzim, or his multiple murder convictions.